AFAP1-Y451 polyclonal, anti-human

AFAP1-Y451 polyclonal, anti-human

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In stock
SKU
AC-AP20714b
Catalog Number: AC-AP20714b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB45038
Applications: WB
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Background:
Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Other Names:
Actin filament-associated protein 1, 110 kDa actin filament-associated protein, AFAP-110, AFAP1, AFAP

Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 444-477 amino acids from human.

Gene Name: AFAP1
Gene ID: 60312
Primary Accession: Q8N556
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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