AFP antibody (clone 1G7), anti-human
€435.00
In stock
SKU
AC-AT1066a
Catalog Number: AC-AT1066a
Size: 100 µg
Isotype: mouse IgG
Applications: WB, IF, IP, E
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Size: 100 µg
Isotype: mouse IgG
Applications: WB, IF, IP, E
Request Information AC-AT1066a">Request Information
Background:
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Other Names:
Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP, HPAFP
Antigen Type:
Recombinant Protein
Gene Name: AFP
Gene ID: 174
NCBI Accession: NP_001125.1
Primary Accession: P02771
Other Accession: BC027881
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Other Names:
Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP, HPAFP
Antigen Type:
Recombinant Protein
Gene Name: AFP
Gene ID: 174
NCBI Accession: NP_001125.1
Primary Accession: P02771
Other Accession: BC027881
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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