AFP (clone 2E1C10), anti-human antibody

Background:
AFP (Alpha-Feto Protein) is a glycoprotein with molecular weight of approximately 70 kDa. It is a major protein in developing fetus and decreases to lower level after birth. In healthy adults, less than 20 ng/ml of AFP is found in the serum. Serum AFP elevates when hepatocellular carcinoma or testicular germ cell tumors occurs. Therefore, it is a useful marker in diagnosing hepatocellular carcinoma and germ cell tumors. In addition, for pregnant women, the AFP concentration is 10-150 ng/ml in the blood. High levels of AFP can indicate a neural tube defect of the fetus, such us spina bifida. AFP Antibody is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with AFP protein purified from human hepatocellular carcinoma

Other Names:
Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP, AFP, Alpha-fetoprotein

Primary Accession: P02771

Gene Name: AFP

Gene ID: 174