AFP polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
AFP, also called Alpha-fetoprotein; alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.

Description:
Rabbit IgG polyclonal antibody for Alpha-fetoprotein (AFP) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
AFP antibody, Alpha fetoglobulin antibody, Alpha fetoprotein antibody, Alpha fetoproteinprecursor antibody, Alpha-1-fetoprotein antibody, Alpha-fetoglobulin antibody, Alpha-fetoprotein antibody, alpha-fetoprotein, Hereditary persistence of, included antibody, FETA antibody, FETA_HUMAN antibody, Hereditary persistence of alpha fetoprotein antibody, HPAFP antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human AFP recombinant protein (Position: Q378-V609). Human AFP shares 71% and 73% amino acid (aa) sequences identity with mouse and rat AFP, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.