AFP Polyclonal Antibody

Background:
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Research Area: Cancer, Cardiovascular, Developmental Biology

Synonyms:
Afp, AFPD, Alpha fetoglobulin, Alpha fetoprotein precursor, Alpha-1-fetoprotein, FETA, Hereditary persistence of alpha fetoprotein, HPAFP

Immunogen: Recombinant Mouse Alpha-fetoprotein protein

Swissprot: P02772

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:100 IF 1:100-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.