AGPAT2 Polyclonal Antibody

Background:
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Cardiovascular, Metabolism

Synonyms:
AGPAT2, 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta

Immunogen: Recombinant fusion protein of human AGPAT2 (NP_006403.2).

Swissprot: O15120
Gene ID: 10555

Calculated MW: 27 kDa/30 kDa
Observed MW: 31 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.