AGR2 polyclonal, anti-human

Background:
AGR2 (Anterior Gradient Protein 2), also known as AG2, GOB-4 or HAG-2, is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and α-dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.

Alternative Name:
AG-2, hAG-2, AGR2, AG 2, AG 2 protein, AG-2, AG2, AG2 protein, AGR 2, AGR2, AGR2, Anterior gradient 2 homolog (Xenopus laevis), anterior gradient 2 homolog, Anterior gradient 2, Xenopus, homolog of, Anterior gradient homolog 2, Anterior gradient protein 2 homolog, GOB 4, GOB4, HAG 2, hAG-2, hAG2, HAG2/R, HPC 8, hPC8, PDIA17, Protein disulfide isomerase family A member 17, secreted cement gland homolog, Secreted cement gland protein XAG 2 homolog, Secreted cement gland protein XAG-2 homolog, Secreted cement gland protein XAG2 homolog, XAG 2, XAG2,

Application Dilution:
WB:1:1,000-1:5,000
ICC:1:100-1:500
IHC:1:50-1:200
FC:1:50-1:100

Specificity: AGR2 polyclonal antibody detects endogenous levels of AGR2 protein.

Immunogen:
recombinant protein

MW: 17 kDa

Swiss-Prot: O95994(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.