AGRN Polyclonal Antibody

Background:
This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found.

Research Area: Neuroscience, Signal Transduction

Synonyms:
AGRIN, Agrin proteoglycan, AGRN, FLJ45064, OTTHUMP00000044043

Immunogen: Synthetic peptide of human AGRN

Swissprot: O00468
Gene Accession: NP_940978

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6166/sc-6040/sc-25528