AGRP Picoband polyclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO12821
Catalog Number: AC-ABO12821
Size: 100 µg
Isotype: Rabbit IgG
Applications: IHC-P, E
Datasheet
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Size: 100 µg
Isotype: Rabbit IgG
Applications: IHC-P, E
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for AGRP detection. Tested with IHC-P, Direct ELISA in Human;Mouse;Rat.
Protein Function:
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity (By similarity). It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner (By similarity).
Other Names: Agouti-related protein, Agrp, Agrt, Art
Subcellular Localization: Secreted.
Tissue Specificity: Expressed in arcuate nucleus and median eminence, adrenal gland (medulla), hypothalamus, testis, and lung.
Gene ID: 11604
Immunogen: E. coli-derived mouse AGRP recombinant protein (Position: S82-T131).
Calculated MW: 14432
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20˚C; for one year. After reconstitution, at 4˚C; for one month. It can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing.
Protein Function:
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity (By similarity). It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner (By similarity).
Other Names: Agouti-related protein, Agrp, Agrt, Art
Subcellular Localization: Secreted.
Tissue Specificity: Expressed in arcuate nucleus and median eminence, adrenal gland (medulla), hypothalamus, testis, and lung.
Gene ID: 11604
Immunogen: E. coli-derived mouse AGRP recombinant protein (Position: S82-T131).
Calculated MW: 14432
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20˚C; for one year. After reconstitution, at 4˚C; for one month. It can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing.
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