AGTR1 polyclonal, anti-human, mouse

Quantity: 100 µg

Background:
AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

Description:
Rabbit IgG polyclonal antibody for Type-1 angiotensin II receptor (AGTR1) detection. Tested with WB, IHC-P in Human, Mouse.

Synonyms:
AG2S antibody, Agtr 1 antibody, Agtr1 antibody, AGTR1_HUMAN antibody, Agtr1a antibody, AGTR1B antibody, Ang II antibody, Angiotensin II receptor type 1 antibody, Angiotensin II type-1 receptor antibody, Angiotensin receptor 1 antibody, Angiotensin receptor 1B antibody, AT 1B antibody, AT 1r antibody, AT1 antibody, At1a antibody, AT1AR antibody, AT1B antibody, AT1BR antibody, AT1R antibody, AT2R1 antibody, AT2R1A antibody, AT2R1B antibody, HAT1R antibody, Type 1 angiotensin II receptor antibody, Type 1B angiotensin II receptor antibody, Type-1 angiotensin II receptor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human AGTR1 (1-28aa MILNSSTEDGIKRIQDDCPKAGRHNYIF), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.