AHR polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.

Synonyms: AHR, bHLHe76, aryl hydrocarbon receptor

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human AHR

Gene Symbol: AHR

Gene ID: 196

Swiss prot: P35869

Calculated MW: 96kDa

Recommended dilution:
WB 1:5200-2000, IHC 1:50-200, IF 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.