AIFM1 polyclonal (N-term), anti-human

AIFM1 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP8910a
Catalog Number: AC-AP8910a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22966
Applications: FC, IHC-P, WB, IF
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Background:
AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.

Other Names:
Apoptosis-inducing factor 1, mitochondrial, 111-, Programmed cell death protein 8, AIFM1, AIF, PDCD8

Target/Specificity:
This AIFM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human AIFM1.

Antigen Region:
70-98

Antigen Type: Synthetic Peptide

Gene Name: AIFM1 (HGNC:8768)
Gene ID: 9131
Primary Accession: O95831
NCBI Accession: NP_001124318.1;NP_001124319.1;NP_004199.1;NP_665811.1;NP_665812.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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