AIMP2 Polyclonal Antibody

Background:
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Research Area: Cancer, Cell Biology, Neuroscience

Synonyms:
Aimp2, AIMP2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Aminoacyl tRNA synthetase complex interacting multifunctional protein 2, ARS interacting multi functional protein 2, JTV 1, JTV 1 protein, JTV1, JTV1 gene, Multisynthase complex auxiliary component p38, Multisynthetase complex auxiliary component p38, P38, PRO0992, Protein JTV 1, Protein JTV-1, tRNA SYNTHETASE COFACTOR p38

Immunogen: Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein

Swissprot: Q13155

Calculated MW: 35 kDa
Observed MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: WB 1:500-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.