AIRE (isoform 1) polyclonal, anti-human, pig

Background:
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Other Names:
Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED

Antigen Types:
Synthetic Peptide

Gene Name:
AIRE
Gene ID:
326
Primary Accession: O43918
Other Accession: NP_000374;326;