AIRE polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP11079c
Catalog Number: AC-AP11079c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30050
Applications: WB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30050
Applications: WB, IF
Datasheet
Request Information
Background:
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
Other Names:
Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED
Target/Specificity:
This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.
Antigen Region:
64-92
Antigen Type: Synthetic Peptide
Gene Name: AIRE
Gene ID: 326
Primary Accession: O43918
NCBI Accession: NP_000374.1
Other Accession: NP_000374.1;NP_000649.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
Other Names:
Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED
Target/Specificity:
This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.
Antigen Region:
64-92
Antigen Type: Synthetic Peptide
Gene Name: AIRE
Gene ID: 326
Primary Accession: O43918
NCBI Accession: NP_000374.1
Other Accession: NP_000374.1;NP_000649.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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