AK1C4 polyclonal antibody, anti-human, mouse, rat

AK1C4 polyclonal antibody, anti-human, mouse, rat

€0.00
In stock
SKU
BT-AP06132
Catalog Number: BT-AP06132
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): WB, ELISA
Datasheet
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Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms: Aldo-keto reductase family 1 member C4 , EC 1.1.1.-, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, EC 1.1.1.50, Chlordecone reductase, CDR, EC 1.1.1.225, Dihydrodiol dehydrogenase 4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year
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