AKAP-10 polyclonal, anti-human
€422.00
In stock
SKU
252015
Protein Family: Receptors and Channels
Pathway and Disease: Signaling Molecules and Interaction
Description:
A-kinase anchor protein 10, mitochondrial (AKAP-10) is a differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one hypothesis that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. PKA, via its RGS domain, provides a link between the signaling machinery and downstream kinaes.
Alternate Names: A kinase anchor protein 10, mitochondrial, AKAP-10, Protein kinase A-anchoring protein 10, PRKA10, Dual specificity A kinase-anchoring protein 2, D-AKAP-2, AKAP10
Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000
Accession No.: O43572
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AKAP-10.
Format: Each vial contains 0.1 mL of crude serum with 0.09% sodium azide.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
A-kinase anchor protein 10, mitochondrial (AKAP-10) is a differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one hypothesis that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. PKA, via its RGS domain, provides a link between the signaling machinery and downstream kinaes.
Alternate Names: A kinase anchor protein 10, mitochondrial, AKAP-10, Protein kinase A-anchoring protein 10, PRKA10, Dual specificity A kinase-anchoring protein 2, D-AKAP-2, AKAP10
Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000
Accession No.: O43572
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AKAP-10.
Format: Each vial contains 0.1 mL of crude serum with 0.09% sodium azide.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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