AKAP10 antibody (clone 8C10), anti-human, mouse
€435.00
In stock
SKU
AC-AT1082a
Catalog Number: AC-AT1082a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT1082a">Request Information
Background:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Other Names:
A-kinase anchor protein 10, mitochondrial, AKAP-10, Dual specificity A kinase-anchoring protein 2, D-AKAP-2, Protein kinase A-anchoring protein 10, PRKA10, AKAP10
Antigen Type:
Recombinant Protein
Gene Name: AKAP10
Gene ID: 11216
NCBI Accession: NP_009133.2
Primary Accession: O43572
Other Accession: NM_007202
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Other Names:
A-kinase anchor protein 10, mitochondrial, AKAP-10, Dual specificity A kinase-anchoring protein 2, D-AKAP-2, Protein kinase A-anchoring protein 10, PRKA10, AKAP10
Antigen Type:
Recombinant Protein
Gene Name: AKAP10
Gene ID: 11216
NCBI Accession: NP_009133.2
Primary Accession: O43572
Other Accession: NM_007202
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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