AKAP14 polyclonal, anti-human, mouse, rat

Background:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Binds to type II regulatory subunits of protein kinase A and anchors/targets them.

Alternative Name:
AKAP-14, AKAP 28, PRKA14, AKAP14, A kinase (PRKA) anchor protein 14, A kinase anchor protein 14, A kinase anchor protein 28 kDa, A-kinase anchoring protein 28, AKAP14, AKAP28, PRKA14, Protein kinase A anchoring protein 14,

Application Dilution:
WB:1:1,000-1:5,000
ICC:1:50-1:200

Specificity: AKAP14 polyclonal antibody detects endogenous levels of AKAP14 protein.

Immunogen:
recombinant protein

MW: 23 kDa

Swiss-Prot: Q86UN6(Human) Unigene:471848(Mouse) O35817(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.