DHRS2 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP51756
Catalog Number: AC-AP54702
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
Datasheet
Request Information
Background:
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Other Names:
Dehydrogenase/reductase SDR family member 2, mitochondrial, 111-, Dicarbonyl reductase HEP27, Protein D, DHRS2
Antigen Type: synthetic peptide
Antigen Type: DHRS2 (HGNC:18349)
Gene ID: 10202
Primary Accession: Q13268
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Other Names:
Dehydrogenase/reductase SDR family member 2, mitochondrial, 111-, Dicarbonyl reductase HEP27, Protein D, DHRS2
Antigen Type: synthetic peptide
Antigen Type: DHRS2 (HGNC:18349)
Gene ID: 10202
Primary Accession: Q13268
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