AKAP7 Polyclonal Antibody

Background:
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[

Research Area: Signal Transduction

Synonyms:
A-Kinase Anchoring Protein 7, A Kinase (PRKA) Anchor Protein 7, A-Kinase Anchor Protein 18 KDa, AKAP 18, AKAP15, AKAP18, Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta, Protein Kinase A-Anchoring Protein 7 Isoform Gamma.

Immunogen: Fusion protein of human AKAP7

Swissprot: O43687
Gene Accession: BC016927

Calculated MW: 11 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.48 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:1000-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.