AKAP8 Polyclonal Antibody

Background:
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.

Research Area: Cancer, Cell Biology

Synonyms:
A kinase (PRKA) anchor protein 8, A kinase anchor protein 8, A kinase anchor protein 95, A kinase anchor protein 95 kDa, A kinase anchor protein 95kDa, A-kinase anchor protein 8, A-kinase anchor protein 95 kDa, AKAP 8, AKAP 95, AKAP-8, AKAP-95, Akap8, AKAP8, AKAP95, DKFZp586B1222

Immunogen: Synthetic peptide of human AKAP8

Swissprot: O43823
Gene Accession: NP_005849

Calculated MW: 76 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6447/sc-161326/sc-10766