AKR1B1 Polyclonal Antibody

Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
ADR, AKR1B 1, Akr1b1, Aldehyde reductase 1, Aldehyde reductase, Aldo keto reductase family 1, member B1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), Aldose reductase, aldr 1, ALDR, aldr1, ALR2, AR, Lii5 2 CTCL tumor antigen, Low Km aldose reductase, MGC1804

Immunogen: Synthetic peptide of human AKR1B1

Swissprot: P15121
Gene Accession: NP_001619

Calculated MW: 36 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-17736/sc-17735/sc-17732/sc-17733/sc-33219