AKR1B1 Polyclonal Antibody

Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
AKR1B1, ADR, ALDR1, ALR2, AR

Immunogen: Recombinant fusion protein of human AKR1B1 (NP_001619.1).

Swissprot: P15121
Gene ID: 231

Calculated MW: 35 kDa
Observed MW: 36.5 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.