AKR1C4 polyclonal, anti-human
€426.00
In stock
SKU
AC-AF1048a
Catalog Number: AC-AF1048a
Size: 100 µg
Isotype: Goat
Applications: WB, IHC, E
Datasheet
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Size: 100 µg
Isotype: Goat
Applications: WB, IHC, E
Datasheet
Request Information
Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Other Names:
Aldo-keto reductase family 1 member C4, 1.1.1.-, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, 1.1.1.357, Chlordecone reductase, CDR, 1.1.1.225, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
Antigen Types:
Synthetic Peptide
Gene Name:
AKR1C4
Gene ID:
1109
Primary Accession: P17516
Other Accession: NP_001809;1109;
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Other Names:
Aldo-keto reductase family 1 member C4, 1.1.1.-, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, 1.1.1.357, Chlordecone reductase, CDR, 1.1.1.225, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
Antigen Types:
Synthetic Peptide
Gene Name:
AKR1C4
Gene ID:
1109
Primary Accession: P17516
Other Accession: NP_001809;1109;
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