AKR1C4 polyclonal, anti-human

Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Synonyms: C11, CDR, DD4, CHDR, DD-4, HAKRA, 3-alpha-HSD

Cellular Location: Cytoplasm

Immunogen:
Full length fusion protein

Gene Symbol: AKR1C4

Gene ID: 1109

Swiss prot: P17516

Calculated MW: 37kDa

Recommended dilution:
WB 1:500-2000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.