AKR1C4 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Synonyms: 3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human AKR1C4

Gene Symbol: AKR1C4

Gene ID: 1109

Swiss prot: P17516

Calculated MW: 37kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.