AKR1D1 Polyclonal Antibody

Background:
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
3-oxo-5-beta-steroid 4-dehydrogenase, 3o5bred, AK1D1, AKR1D1, aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase), Aldo keto reductase family 1 member D1, Aldo-keto reductase family 1 member D1, CBAS2, Delta(4) 3 ketosteroid 5 beta reductase, Delta(4) 3 oxosteroid 5 beta reductase, Delta(4)-3-ketosteroid 5-beta-reductase, Delta(4)-3-oxosteroid 5-beta-reductase, SRD5B1, steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1), steroid 5 beta reductase

Immunogen: Recombinant protein of human AKR1D1

Swissprot: P51857
Gene Accession: BC130625

Calculated MW: 37 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-67709/sc-67709/sc-67710/sc-67711/sc-134968