AKR7A2 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Synonyms: AFAR, AFAR1, AFB1-AR1, AKR7

Cellular Location: Cytoplasm Golgi apparatus

Immunogen:
Recombinant protein of human AKR7A2

Gene Symbol: AKR7A2

Gene ID: 8574

Swiss prot: O43488

Calculated MW: 40kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.