AKR7A2 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Research Area: Metabolism, Neuroscience, Signal Transduction

Synonyms:
AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7

Immunogen: Recombinant fusion protein of human AKR7A2 (NP_003680.2).

Swissprot: O43488
Gene ID: 8574

Calculated MW: 39 kDa
Observed MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.