AKT rabbit polyclonal, anti-human, mouse, rat

Backgroud: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Synonyms: AKT1

Gene Name: AKT1/AKT2/AKT3

Gene ID: 207/208/10000

SwissProt ID: P31749/P31751/Q9Y243

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.