AKT2 polyclonal, anti-human, mouse, rat

Background:
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Synonyms: HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA

Cellular Location: Cell membrane Cytoplasm Early endosome Nucleus Peripheral membrane protein

Immunogen:
A synthetic peptide of human AKT2

Gene Symbol: AKT2

Gene ID: 208

Swiss prot: P31751

Calculated MW: 56kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.