AKT2 Polyclonal Antibody

Background:
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
Akt2, AKT2, HIHGHH, murine thymoma viral (v-akt) homolog-2, PKB, PKB beta, PKBB, PKBBETA, PRKBB, Protein kinase Akt 2, Protein kinase Akt-2, Protein kinase B beta, rac protein kinase beta, RAC-BETA, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, v akt murine thymoma viral oncogene homolog 2

Immunogen: Synthetic peptide of human AKT2

Swissprot: P31751
Gene Accession: NP_001617

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7127