AKT2 polyclonal (Center), anti-human

AKT2 polyclonal (Center), anti-human

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In stock
SKU
AC-AP7029c
Catalog Number: AC-AP7029c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3026
Applications: IHC-P, FC, IF, WB
Datasheet

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Background:
AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.

Other Names:
RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, Protein kinase B beta, PKB beta, RAC-PK-beta, AKT2

Target/Specificity:
This AKT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-123 amino acids from the Central region of human AKT2.

Antigen Region:
93-123

Antigen Type: Synthetic Peptide

Gene Name: AKT2 (HGNC:392)
Gene ID: 208
Primary Accession: P31751
NCBI Accession: NP_001617.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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