Akt3 (clone 3B12F3F10; 2D2B11B11; 2D2B11H5), anti-human

Akt3 (clone 3B12F3F10; 2D2B11B11; 2D2B11H5), anti-human

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In stock
SKU
BT-MCA2651
Catalog Number: BT-MCA2651
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, ELISA
Datasheet
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Background:
Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.

Research Area: Neuroscience, Cardiovascular

Synonyms: Akt3

Immunogen: Purified recombinant fragment of Akt3 expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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