AKTIP polyclonal(C-term), anti-human
€0.00
In stock
SKU
AC-AP19369b
Catalog Number: AC-AP19369b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38675
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38675
Applications: WB
Datasheet
Request Information
Background:
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
Other Names:
AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS
Target/Specificity:
This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.
Antigen Region:
262-288
Antigen Type: Synthetic Peptide
Gene Name: AKTIP (HGNC:16710)
Gene ID: 64400
Primary Accession: Q9H8T0
NCBI Accession: NP_001012398.1;NP_071921.1
Other Accession: Q5FVH4; Q64362; Q4R5E1; Q5ZJJ5; NP_001012398.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
Other Names:
AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS
Target/Specificity:
This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.
Antigen Region:
262-288
Antigen Type: Synthetic Peptide
Gene Name: AKTIP (HGNC:16710)
Gene ID: 64400
Primary Accession: Q9H8T0
NCBI Accession: NP_001012398.1;NP_071921.1
Other Accession: Q5FVH4; Q64362; Q4R5E1; Q5ZJJ5; NP_001012398.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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