ALAD polyclonal (C-term), anti-human
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In stock
SKU
AC-AP6828b
Catalog Number: AC-AP6828b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20913
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20913
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.
Other Names:
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase, ALAD
Target/Specificity:
This ALAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-272 amino acids from the C-terminal region of human ALAD.
Antigen Region:
244-272
Antigen Type: Synthetic Peptide
Gene Name: ALAD
Gene ID: 210
Primary Accession: P13716
NCBI Accession: NP_000022.3
Other Accession: Q60HH9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.
Other Names:
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase, ALAD
Target/Specificity:
This ALAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-272 amino acids from the C-terminal region of human ALAD.
Antigen Region:
244-272
Antigen Type: Synthetic Peptide
Gene Name: ALAD
Gene ID: 210
Primary Accession: P13716
NCBI Accession: NP_000022.3
Other Accession: Q60HH9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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