ALDH1A1/2/3 Polyclonal Antibody

Background:
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Research Area: Cancer, Neuroscience, Stem Cells

Synonyms:
ALDC, ALDH1, PUMB1, ALDH11, RALDH1, ALDH-E1, RALDH2, RALDH2-T, RALDH(II), ALDH6, RALDH3, ALDH1A6

Immunogen: Recombinant protein of human ALDH1A1/ALDH1A2/ALDH1A3

Swissprot: P00352,O94788,P47895
Gene Accession: BC001505/BC030589/BC069274

Calculated MW: 57 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:150

Storage:
Store at -20°C. Avoid freeze / thaw cycles.