ALDH1A1/ALDH1A2/ALDH1A3 polyclonal, anti-human

Background:
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms: ALDC, ALDH1, PUMB1, ALDH11, RALDH1, ALDH-E1, RALDH2, RALDH2-T, RALDH(II), ALDH6, RALDH3, ALDH1A6

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human ALDH1A1/ALDH1A2/ALDH1A3

Gene Symbol: ALDH1A1/ALDH1A2/ALDH1A3

Gene ID: 216/8854/220

Swiss prot: P00352/O94788/P47895

Calculated MW: 57kDa

Recommended dilution:
WB 1:500-1000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.