ALDH1A1 polyclonal (Center), anti-human

ALDH1A1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP1465C
Catalog Number: AC-AP1465C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13004
Applications: WB, IF, IHC-P, FC
Datasheet

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Background:
ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.

Other Names:
Retinal dehydrogenase 1, RALDH 1, RalDH1, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, ALDH1A1, ALDC, ALDH1, PUMB1

Target/Specificity:
This ALDH1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the Central region of human ALDH1A1.

Antigen Region:
302-331

Antigen Type: Synthetic Peptide

Gene Name: ALDH1A1 (HGNC:402)
Gene ID: 216
Primary Accession: P00352
NCBI Accession: NP_000680.2
Other Accession: O35945; Q8HYE4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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