ALDH1A2 Polyclonal Antibody

Background:
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Research Area: Cancer, Developmental Biology, Neuroscience

Synonyms:
AL1A2, Aldehyde dehydrogenase family 1 member A2, ALDH1A2 aldehyde dehydrogenase 1 family, member A2, ALDH1A2, Aldh1a7, AV116159, MGC26444, RALDH 2, RALDH(II), Raldh1, RalDH2, RALDH2 T, Retinal dehydrogenase 2, Retinaldehyde dehydrogenase 2, Retinaldehyde specific dehydrogenase type 2, Retinaldehyde-specific dehydrogenase type 2

Immunogen: Synthetic peptide of human ALDH1A2

Swissprot: O94788
Gene Accession: NP_001193826

Calculated MW: 57 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-22591