ALDH1B1 rabbit polyclonal, anti-human, monkey

Backgroud: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008],catalytic activity:An aldehyde + NAD(+) + H(2)O = an acid + NADH.,function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer.,tissue specificity:Liver, testis and to a lesser extent in brain.,

Synonyms: ALDH1B1, ALDH5, ALDHX, Aldehyde dehydrogenase X, mitochondrial, Aldehyde dehydrogenase 5, Aldehyde dehydrogenase family 1 member B1

Gene Name: ALDH1B1

Gene ID: 219

SwissProt ID: P30837

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.