ALDH1L1 (clone 1B5E1), anti-human, mouse, rat

Background:
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cell biology, Metabolism, Neuroscience, Signal transduction

Synonyms: FDH, FTHFD, 10-fTHF, 10-FTHFDH

Immunogen: Purified recombinant fragment of human ALDH1L1 (AA: 10-222) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage