ALDH2 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM1831a
Catalog Number: AC-AM1831a
Size: 80 µl, 400 µl
Isotype: mouse IgG1,Igκ
Clone Name: 138CT22.3.8
Applications: WB, IF, FC, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1,Igκ
Clone Name: 138CT22.3.8
Applications: WB, IF, FC, IHC-P
Datasheet
Request Information
Background:
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.
Other Names:
Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH-E2, ALDHI, ALDH2, ALDM
Target/Specificity:
This ALDH2 Monoclonal antibody is generated from mouse immunized with ALDH2 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: ALDH2
Gene ID: 217
Primary Accession: P05091
NCBI Accession: NP_000681.2;NP_001191818.1
Other Accession: NP_000681
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.
Other Names:
Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH-E2, ALDHI, ALDH2, ALDM
Target/Specificity:
This ALDH2 Monoclonal antibody is generated from mouse immunized with ALDH2 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: ALDH2
Gene ID: 217
Primary Accession: P05091
NCBI Accession: NP_000681.2;NP_001191818.1
Other Accession: NP_000681
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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