ALDH4A1 Polyclonal Antibody

Background:
This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
AL4A1, aldehyde dehydrogenase 4, aldehyde dehydrogenase 4 family, member A1, Aldehyde dehydrogenase family 4 member A1, Aldehyde dehydrogenase, family 4, subfamily A, member 1, ALDH4, aldh4a1, Delta 1 pyrroline 5 carboxylate dehydrogenase, mitochondrial, Delta-1-pyrroline-5-carboxylate dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase, mitochondrial, mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase, P5C dehydrogenase, P5CD, P5CDh, P5CDhL, P5CDhS, Pyrroline-5-carboxylate dehydrogenase, RP11 128M10.1

Immunogen: Recombinant protein of human ALDH4A1

Swissprot: P30038
Gene Accession: BC007581

Calculated MW: 62 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-69145/sc-130948