ALDH6A1 Polyclonal Antibody

Background:
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
1110038I05Rik, AI314632, Aldehyde dehydrogenase 6 family member A1, Aldehyde dehydrogenase family 6 member A1, Aldehyde dehydrogenase family 6, subfamily A1, ALDH6A1, Malonate semialdehyde dehydrogenase, Malonate-semialdehyde dehydrogenase [acylating], Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial, Methylmalonate-semialdehyde dehydrogenase [acylating], MGC37325, MGC40271, Mitochondrial acylating methylmalonate semialdehyde dehydrogenase, mitochondrial, MMSA, MMSADHA, MMSDH

Immunogen: Recombinant protein of human ALDH6A1

Swissprot: Q02252
Gene Accession: BC004909

Calculated MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-107137/sc-107138/sc-292507