ALDH7A1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.

Synonyms: ATQ1, EPD, PDE

Cellular Location: Cytoplasm Mitochondrion Nucleus cytosol

Immunogen:
Recombinant protein of human ALDH7A1

Gene Symbol: ALDH7A1

Gene ID: 501

Swiss prot: P49419

Calculated MW: 58kDa

Recommended dilution:
WB 1:1000-4000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.