ALDOA polyclonal, anti-human, mouse

Background:
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Synonyms: ALDA, GSD12, HEL-S-87p

Cellular Location: Cytoplasm I band M line myofibril sarcomere

Immunogen:
Recombinant protein of human ALDOA

Gene Symbol: ALDOA

Gene ID: 226

Swiss prot: P04075

Calculated MW: 39kDa

Recommended dilution:
WB 1:500-2000, IF 1:20-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.