ALDOA Polyclonal Antibody

Background:
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
ALDA, Aldo1, ALDOA, ALDOA, Aldolase 1, Aldolase A, Aldolase A fructose bisphosphatase, Aldolase A fructose bisphosphate, Aldolase, fructose-bisphosphate A, Epididymis secretory sperm binding protein Li 87p, FRUCTOALDOLASE A, Fructose 1 6 bisphosphate triosephosphate lyase, Fructose bisphosphate aldolase A, Fructose bisphosphate aldolase, FRUCTOSE-1, 6-BISPHOSPHATE ALDOLASE A, Fructose-bisphosphate aldolase A, Fructose-bisphosphate aldolase A Muscle-type, GSD12, HEL S 87p, Lung cancer antigen NY LU 1, Lung cancer antigen NY-LU-1, MGC10942, MGC17716, MGC17767, Muscle type aldolase, Muscle-type aldolase, RNALDOG5

Immunogen: Recombinant protein of human ALDOA

Swissprot: P04075
Gene Accession: BC004333

Calculated MW: 39 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-12061/sc-12059/sc-30082