ALDOB polyclonal (N-term), anti-human
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In stock
SKU
AC-AP18830a
Catalog Number: AC-AP18830a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39475
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39475
Applications: WB
Datasheet
Request Information
Background:
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq].
Other Names:
Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Target/Specificity:
This ALDOB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human ALDOB.
Antigen Region:
31-60
Antigen Type: Synthetic Peptide
Gene Name: ALDOB {ECO:0000303|PubMed:15880727, ECO:0000312|HGNC:HGNC:417}
Gene ID: 229
Primary Accession: P05062
NCBI Accession: NP_000026.2
Other Accession: P00884; P79226; Q91Y97; Q3T0S5; NP_000026.2; P52210
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq].
Other Names:
Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Target/Specificity:
This ALDOB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human ALDOB.
Antigen Region:
31-60
Antigen Type: Synthetic Peptide
Gene Name: ALDOB {ECO:0000303|PubMed:15880727, ECO:0000312|HGNC:HGNC:417}
Gene ID: 229
Primary Accession: P05062
NCBI Accession: NP_000026.2
Other Accession: P00884; P79226; Q91Y97; Q3T0S5; NP_000026.2; P52210
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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